Prognostic Factors for Severe Acute Respiratory Syndrome: A Clinical Analysis of 165 Cases
Identifieur interne : 005538 ( Main/Exploration ); précédent : 005537; suivant : 005539Prognostic Factors for Severe Acute Respiratory Syndrome: A Clinical Analysis of 165 Cases
Auteurs : Zhengsheng Zou [République populaire de Chine] ; Yongping Yang [République populaire de Chine] ; Jumei Chen [République populaire de Chine] ; Shaojie Xin [République populaire de Chine] ; Wei Zhang [République populaire de Chine] ; Xianzhi Zhou [République populaire de Chine] ; Yuanli Mao [République populaire de Chine] ; Liangping Hu [République populaire de Chine] ; Daojian Liu [République populaire de Chine] ; Binxia Chang [République populaire de Chine] ; Weihua Chang [République populaire de Chine] ; Yanping Liu [République populaire de Chine] ; Xuemei Ma [République populaire de Chine] ; Yedong Wang [République populaire de Chine] ; Xiqing Liu [République populaire de Chine]Source :
- Clinical Infectious Diseases [ 1058-4838 ] ; 2004.
Abstract
This study analyzes single factors that affect the prognosis of severe acute respiratory syndrome (SARS) and establishes a prognosis model by multivariate analysis. We retrospectively analyzed the clinical features of SARS in 165 clinically confirmed severe cases. Both age and existence of other diseases before SARS were significantly correlated with prognosis (r = 0.506 and r = 0.457, respectively; P < .001). During the acute phase of SARS, lactate dehydrogenase level, degree of hypoxemia, respiratory rate, α-hydroxybutyric dehydrogenase level, creatine kinase isoenzyme—MB, platelet count, and number of involved lobes noted on chest radiographs, and so on, correlated markedly with the prognosis (r = 0.257–0.788; P < .05). The multivariate prognosis regression model was associated with degree of hypoxemia and platelet count. The model was defined by the formula Py=1 = es/(1 + es), where S is [2.490 × degree of hypoxemia]-[0.050 × number of platelets], and it had a high sensitivity (91.67%), specificity (98.33%), and accuracy (96.42%). The model could be used to effectively judge the state of illness and the prognosis.
Url:
DOI: 10.1086/380973
Affiliations:
Links toward previous steps (curation, corpus...)
- to stream Istex, to step Corpus: 000B03
- to stream Istex, to step Curation: 000B03
- to stream Istex, to step Checkpoint: 001C16
- to stream Main, to step Merge: 005984
- to stream Main, to step Curation: 005538
Le document en format XML
<record><TEI wicri:istexFullTextTei="biblStruct"><teiHeader><fileDesc><titleStmt><title>Prognostic Factors for Severe Acute Respiratory Syndrome: A Clinical Analysis of 165 Cases</title><author><name sortKey="Zou, Zhengsheng" sort="Zou, Zhengsheng" uniqKey="Zou Z" first="Zhengsheng" last="Zou">Zhengsheng Zou</name></author><author><name sortKey="Yang, Yongping" sort="Yang, Yongping" uniqKey="Yang Y" first="Yongping" last="Yang">Yongping Yang</name></author><author><name sortKey="Chen, Jumei" sort="Chen, Jumei" uniqKey="Chen J" first="Jumei" last="Chen">Jumei Chen</name></author><author><name sortKey="Xin, Shaojie" sort="Xin, Shaojie" uniqKey="Xin S" first="Shaojie" last="Xin">Shaojie Xin</name></author><author><name sortKey="Zhang, Wei" sort="Zhang, Wei" uniqKey="Zhang W" first="Wei" last="Zhang">Wei Zhang</name></author><author><name sortKey="Zhou, Xianzhi" sort="Zhou, Xianzhi" uniqKey="Zhou X" first="Xianzhi" last="Zhou">Xianzhi Zhou</name></author><author><name sortKey="Mao, Yuanli" sort="Mao, Yuanli" uniqKey="Mao Y" first="Yuanli" last="Mao">Yuanli Mao</name></author><author><name sortKey="Hu, Liangping" sort="Hu, Liangping" uniqKey="Hu L" first="Liangping" last="Hu">Liangping Hu</name></author><author><name sortKey="Liu, Daojian" sort="Liu, Daojian" uniqKey="Liu D" first="Daojian" last="Liu">Daojian Liu</name></author><author><name sortKey="Chang, Binxia" sort="Chang, Binxia" uniqKey="Chang B" first="Binxia" last="Chang">Binxia Chang</name></author><author><name sortKey="Chang, Weihua" sort="Chang, Weihua" uniqKey="Chang W" first="Weihua" last="Chang">Weihua Chang</name></author><author><name sortKey="Liu, Yanping" sort="Liu, Yanping" uniqKey="Liu Y" first="Yanping" last="Liu">Yanping Liu</name></author><author><name sortKey="Ma, Xuemei" sort="Ma, Xuemei" uniqKey="Ma X" first="Xuemei" last="Ma">Xuemei Ma</name></author><author><name sortKey="Wang, Yedong" sort="Wang, Yedong" uniqKey="Wang Y" first="Yedong" last="Wang">Yedong Wang</name></author><author><name sortKey="Liu, Xiqing" sort="Liu, Xiqing" uniqKey="Liu X" first="Xiqing" last="Liu">Xiqing Liu</name></author></titleStmt><publicationStmt><idno type="wicri:source">ISTEX</idno><idno type="RBID">ISTEX:6FF2A0456DBCF673985B6E771A69A454C5D341F9</idno><date when="2004" year="2004">2004</date><idno type="doi">10.1086/380973</idno><idno type="url">https://api.istex.fr/ark:/67375/HXZ-3B8NR7QM-J/fulltext.pdf</idno><idno type="wicri:Area/Istex/Corpus">000B03</idno><idno type="wicri:explorRef" wicri:stream="Istex" wicri:step="Corpus" wicri:corpus="ISTEX">000B03</idno><idno type="wicri:Area/Istex/Curation">000B03</idno><idno type="wicri:Area/Istex/Checkpoint">001C16</idno><idno type="wicri:explorRef" wicri:stream="Istex" wicri:step="Checkpoint">001C16</idno><idno type="wicri:doubleKey">1058-4838:2004:Zou Z:prognostic:factors:for</idno><idno type="wicri:Area/Main/Merge">005984</idno><idno type="wicri:Area/Main/Curation">005538</idno><idno type="wicri:Area/Main/Exploration">005538</idno></publicationStmt><sourceDesc><biblStruct><analytic><title level="a" type="main">Prognostic Factors for Severe Acute Respiratory Syndrome: A Clinical Analysis of 165 Cases</title><author><name sortKey="Zou, Zhengsheng" sort="Zou, Zhengsheng" uniqKey="Zou Z" first="Zhengsheng" last="Zou">Zhengsheng Zou</name><affiliation wicri:level="3"><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Department of Infectious Diseases, Beijing Infectious Disease Institute of People's Liberation Army, Beijing</wicri:regionArea><placeName><settlement type="city">Pékin</settlement></placeName></affiliation></author><author><name sortKey="Yang, Yongping" sort="Yang, Yongping" uniqKey="Yang Y" first="Yongping" last="Yang">Yongping Yang</name><affiliation wicri:level="3"><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Department of Infectious Diseases, Beijing Infectious Disease Institute of People's Liberation Army, Beijing</wicri:regionArea><placeName><settlement type="city">Pékin</settlement></placeName></affiliation><affiliation></affiliation><affiliation></affiliation></author><author><name sortKey="Chen, Jumei" sort="Chen, Jumei" uniqKey="Chen J" first="Jumei" last="Chen">Jumei Chen</name><affiliation wicri:level="3"><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Department of Infectious Diseases, Beijing Infectious Disease Institute of People's Liberation Army, Beijing</wicri:regionArea><placeName><settlement type="city">Pékin</settlement></placeName></affiliation></author><author><name sortKey="Xin, Shaojie" sort="Xin, Shaojie" uniqKey="Xin S" first="Shaojie" last="Xin">Shaojie Xin</name><affiliation wicri:level="3"><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Department of Infectious Diseases, Beijing Infectious Disease Institute of People's Liberation Army, Beijing</wicri:regionArea><placeName><settlement type="city">Pékin</settlement></placeName></affiliation></author><author><name sortKey="Zhang, Wei" sort="Zhang, Wei" uniqKey="Zhang W" first="Wei" last="Zhang">Wei Zhang</name><affiliation wicri:level="3"><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Department of Infectious Diseases, Beijing Infectious Disease Institute of People's Liberation Army, Beijing</wicri:regionArea><placeName><settlement type="city">Pékin</settlement></placeName></affiliation></author><author><name sortKey="Zhou, Xianzhi" sort="Zhou, Xianzhi" uniqKey="Zhou X" first="Xianzhi" last="Zhou">Xianzhi Zhou</name><affiliation wicri:level="3"><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Department of Infectious Diseases, Beijing Infectious Disease Institute of People's Liberation Army, Beijing</wicri:regionArea><placeName><settlement type="city">Pékin</settlement></placeName></affiliation></author><author><name sortKey="Mao, Yuanli" sort="Mao, Yuanli" uniqKey="Mao Y" first="Yuanli" last="Mao">Yuanli Mao</name><affiliation wicri:level="3"><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Department of Infectious Diseases, Beijing Infectious Disease Institute of People's Liberation Army, Beijing</wicri:regionArea><placeName><settlement type="city">Pékin</settlement></placeName></affiliation></author><author><name sortKey="Hu, Liangping" sort="Hu, Liangping" uniqKey="Hu L" first="Liangping" last="Hu">Liangping Hu</name><affiliation wicri:level="3"><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Institute of Intelligence, Academy of Military Medical Sciences, Beijing</wicri:regionArea><placeName><settlement type="city">Pékin</settlement></placeName></affiliation></author><author><name sortKey="Liu, Daojian" sort="Liu, Daojian" uniqKey="Liu D" first="Daojian" last="Liu">Daojian Liu</name><affiliation wicri:level="3"><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Department of Infectious Diseases, Beijing Infectious Disease Institute of People's Liberation Army, Beijing</wicri:regionArea><placeName><settlement type="city">Pékin</settlement></placeName></affiliation></author><author><name sortKey="Chang, Binxia" sort="Chang, Binxia" uniqKey="Chang B" first="Binxia" last="Chang">Binxia Chang</name><affiliation wicri:level="3"><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Department of Infectious Diseases, Beijing Infectious Disease Institute of People's Liberation Army, Beijing</wicri:regionArea><placeName><settlement type="city">Pékin</settlement></placeName></affiliation></author><author><name sortKey="Chang, Weihua" sort="Chang, Weihua" uniqKey="Chang W" first="Weihua" last="Chang">Weihua Chang</name><affiliation wicri:level="3"><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Department of Infectious Diseases, Beijing Infectious Disease Institute of People's Liberation Army, Beijing</wicri:regionArea><placeName><settlement type="city">Pékin</settlement></placeName></affiliation></author><author><name sortKey="Liu, Yanping" sort="Liu, Yanping" uniqKey="Liu Y" first="Yanping" last="Liu">Yanping Liu</name><affiliation wicri:level="3"><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Department of Infectious Diseases, Beijing Infectious Disease Institute of People's Liberation Army, Beijing</wicri:regionArea><placeName><settlement type="city">Pékin</settlement></placeName></affiliation></author><author><name sortKey="Ma, Xuemei" sort="Ma, Xuemei" uniqKey="Ma X" first="Xuemei" last="Ma">Xuemei Ma</name><affiliation wicri:level="3"><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Department of Infectious Diseases, Beijing Infectious Disease Institute of People's Liberation Army, Beijing</wicri:regionArea><placeName><settlement type="city">Pékin</settlement></placeName></affiliation></author><author><name sortKey="Wang, Yedong" sort="Wang, Yedong" uniqKey="Wang Y" first="Yedong" last="Wang">Yedong Wang</name><affiliation wicri:level="3"><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Department of Infectious Diseases, Beijing Infectious Disease Institute of People's Liberation Army, Beijing</wicri:regionArea><placeName><settlement type="city">Pékin</settlement></placeName></affiliation></author><author><name sortKey="Liu, Xiqing" sort="Liu, Xiqing" uniqKey="Liu X" first="Xiqing" last="Liu">Xiqing Liu</name><affiliation wicri:level="3"><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Department of Infectious Diseases, Beijing Infectious Disease Institute of People's Liberation Army, Beijing</wicri:regionArea><placeName><settlement type="city">Pékin</settlement></placeName></affiliation></author></analytic><monogr></monogr><series><title level="j" type="main">Clinical Infectious Diseases</title><title level="j" type="abbrev">Clinical Infectious Diseases</title><idno type="ISSN">1058-4838</idno><idno type="eISSN">1537-6591</idno><imprint><publisher>The University of Chicago Press</publisher><date type="published">2004</date><biblScope unit="vol">38</biblScope><biblScope unit="issue">4</biblScope><biblScope unit="page" from="483">483</biblScope><biblScope unit="page" to="489">489</biblScope></imprint><idno type="ISSN">1058-4838</idno></series></biblStruct></sourceDesc><seriesStmt><idno type="ISSN">1058-4838</idno></seriesStmt></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract">This study analyzes single factors that affect the prognosis of severe acute respiratory syndrome (SARS) and establishes a prognosis model by multivariate analysis. We retrospectively analyzed the clinical features of SARS in 165 clinically confirmed severe cases. Both age and existence of other diseases before SARS were significantly correlated with prognosis (r = 0.506 and r = 0.457, respectively; P < .001). During the acute phase of SARS, lactate dehydrogenase level, degree of hypoxemia, respiratory rate, α-hydroxybutyric dehydrogenase level, creatine kinase isoenzyme—MB, platelet count, and number of involved lobes noted on chest radiographs, and so on, correlated markedly with the prognosis (r = 0.257–0.788; P < .05). The multivariate prognosis regression model was associated with degree of hypoxemia and platelet count. The model was defined by the formula Py=1 = es/(1 + es), where S is [2.490 × degree of hypoxemia]-[0.050 × number of platelets], and it had a high sensitivity (91.67%), specificity (98.33%), and accuracy (96.42%). The model could be used to effectively judge the state of illness and the prognosis.</div></front></TEI><affiliations><list><country><li>République populaire de Chine</li></country><settlement><li>Pékin</li></settlement></list><tree><country name="République populaire de Chine"><noRegion><name sortKey="Zou, Zhengsheng" sort="Zou, Zhengsheng" uniqKey="Zou Z" first="Zhengsheng" last="Zou">Zhengsheng Zou</name></noRegion><name sortKey="Chang, Binxia" sort="Chang, Binxia" uniqKey="Chang B" first="Binxia" last="Chang">Binxia Chang</name><name sortKey="Chang, Weihua" sort="Chang, Weihua" uniqKey="Chang W" first="Weihua" last="Chang">Weihua Chang</name><name sortKey="Chen, Jumei" sort="Chen, Jumei" uniqKey="Chen J" first="Jumei" last="Chen">Jumei Chen</name><name sortKey="Hu, Liangping" sort="Hu, Liangping" uniqKey="Hu L" first="Liangping" last="Hu">Liangping Hu</name><name sortKey="Liu, Daojian" sort="Liu, Daojian" uniqKey="Liu D" first="Daojian" last="Liu">Daojian Liu</name><name sortKey="Liu, Xiqing" sort="Liu, Xiqing" uniqKey="Liu X" first="Xiqing" last="Liu">Xiqing Liu</name><name sortKey="Liu, Yanping" sort="Liu, Yanping" uniqKey="Liu Y" first="Yanping" last="Liu">Yanping Liu</name><name sortKey="Ma, Xuemei" sort="Ma, Xuemei" uniqKey="Ma X" first="Xuemei" last="Ma">Xuemei Ma</name><name sortKey="Mao, Yuanli" sort="Mao, Yuanli" uniqKey="Mao Y" first="Yuanli" last="Mao">Yuanli Mao</name><name sortKey="Wang, Yedong" sort="Wang, Yedong" uniqKey="Wang Y" first="Yedong" last="Wang">Yedong Wang</name><name sortKey="Xin, Shaojie" sort="Xin, Shaojie" uniqKey="Xin S" first="Shaojie" last="Xin">Shaojie Xin</name><name sortKey="Yang, Yongping" sort="Yang, Yongping" uniqKey="Yang Y" first="Yongping" last="Yang">Yongping Yang</name><name sortKey="Zhang, Wei" sort="Zhang, Wei" uniqKey="Zhang W" first="Wei" last="Zhang">Wei Zhang</name><name sortKey="Zhou, Xianzhi" sort="Zhou, Xianzhi" uniqKey="Zhou X" first="Xianzhi" last="Zhou">Xianzhi Zhou</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Sante/explor/SrasV1/Data/Main/Exploration
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 005538 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd -nk 005538 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Sante
|area= SrasV1
|flux= Main
|étape= Exploration
|type= RBID
|clé= ISTEX:6FF2A0456DBCF673985B6E771A69A454C5D341F9
|texte= Prognostic Factors for Severe Acute Respiratory Syndrome: A Clinical Analysis of 165 Cases
}}
| This area was generated with Dilib version V0.6.33. |  |